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Shaw, Gwo-Chyuan
  • Education:Ph.D. Biochemistry, University of California, Los Angeles
  • Office: R506, 5F, Tradition Medicine Building
  • Phone: 886-2-28267127
  • Email: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
  • Personal Web Site
  • Research--Identification of functional genes involved in PHB metabolism and regulation of gene expression in Bacillus spp.
  • Signal transduction and regulation of expression of genes involved in biosynthesis and mobilization of poly(3-hydroxybutyrate) (PHB) in Bacillus spp..
  • Mechanisms for induction of Bacillus genes in response to a variety of environmental stress conditions.
  • Identification and characterization of novel DNA-binding proteins and enzymes of Bacillus spp..
  • Publications
    • Chen, H.J., Tsai, T.K., Pan, S.C., Lin, J.S., Tseng, C.L., Shaw, G.C. (2010) The master transcription factor Spo0A is required for poly(3-hydroxybutyrate) (PHB) accumulation and expression of genes involved in PHB biosynthesis in Bacillus thuringiensis. FEMS Microbiol Lett. 304:74-81.

    • Chen, H.J., Pan, S.C., Shaw, G.C. (2009) Identification and characterization of a novel intracellular poly(3-hydroxybutyrate) depolymerase from Bacillus megaterium. Appl. Environ. Microbiol. 75:5290-5299.

    • Tseng, C.L. and Shaw, G.C. (2008) Genetic evidence for the actin homolog gene mreBH and the bacitracin resistance gene bcrC as targets of the alternative sigma factor SigI of Bacillus subtilis. J. Bacteriol. 190:1561-1567.

    • Lin, J.S. and Shaw, G.C. (2007) Regulation of the kduID operon of Bacillus subtilis by the KdgR repressor and the ccpA gene: identification of two KdgR-binding sites within the kdgR-kduI intergenic region. Microbiology 153:701-710.

    • Tseng, C.L., Chen, H.J., and Shaw, G.C. (2006) Identification and characterization of the Bacillus thuringiensis phaZ gene, encoding new intracellular poly(3-hydroxybutyrate) depolymerase. J. Bacteriol. 188:7592-7599.

    • Li, J.M., Chiou, C.Y., Lee, T.R., Chen, Y.S., and Shaw, G.C. (2005) Identification of a lactose-responsive element upstream of the promoter of Bacillus megaterium β-galactosidase-encoding gene mbgA. Curr. Microbiol. 51:31-34.

    • Shaw, G.C., Wu, M.Y., Lee, T.R., and Hsu, C.W. (2005) The influence of nucleotide sequences at and near ribosome-binding site on translational efficiency of the Bacillus subtilis rho gene. Biochim. Biophys. Acta 1729:10-13.

    • Lee, T.R., Lin, J.S., Wang, S.S., and Shaw, G.C. (2004) PhaQ, a new class of poly(3-hydroxybutyrate) (PHB)-responsive repressor, regulates phaQ and phaP (phasin) expression in Bacillus megaterium through interaction with PHB. J. Bacteriol. 186:3015-3021.

    • Chiou, C.Y., Wang, H.H., Shaw, G.C. (2002) Identification and characterization of the non-PTS fru locus of Bacillus megaterium ATCC 14581. Mol. Genet. Genomics 268:240-248.

    • Shaw, G.C., Chiou, C.Y., Chou, Y.H., and Li, J.M. (2002) mbgA-dependent lactose utilization by Bacillus megaterium. Curr. Microbiol. 44:102-105.

    • Lee, T.R., Hsu, H.P., and Shaw, G.C. (2001) Transcriptional regulation of the Bacillus subtilis bscR-CYP102A3 operon by the BscR repressor and differential induction of cytochrome CYP102A3 expression by oleic acid and palmitate. J. Biochem. 130:569-574.

    • Shaw, G.C., Hsueh, Y.H., Sung, C.C., Chen, Y.S., and Liu, C.H. (2000) Negative regulation of expression of the Bacillus megaterium bm1P1 gene by the bm1P1 3' flanking region. J. Bacteriol. 182, 2654-2659.

    • Shaw, G.C., Hsueh, Y.H., and Kao, H.S. (2000) The basal-level expression of the cytochrome P450BM-1 gene is negatively affected by the bm1P1 gene of Bacillus megaterium. Curr. Microbiol. 40, 47-50.

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